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副高级人员

徐文忠

副研究员

所属部门:

中国科学院植物研究所

研究方向:

特色经济作物快速驯化与改良

邮箱:

xuwzh@ibcas.ac.cn

通讯地址:

北京市海淀区香山南辛村20号

简历介绍

教育经历

1996年,湖南农业大学大学获农学学士学位;

1999年,中国农业大学大学获理学硕士学位;

2003年,中国科学院植物研究所获理学博士学位;

工作经历

2013年-2014年,在美国做访问学者;

2003年至今,在中国科学院植物研究所历任研究实习员、助理研究员、副研究员。

研究方向

    长期从事从事植物逆境分子生物学与基因组编辑技术等研究。主要包括:1)资源植物基因组编辑育种;2)植物吸收、转运重金属及信号应答的分子机理。研究在Molecular Plant、New Phytologist、Plant, Cell & Environment、Environmental Science & Technology等国际重要学术期刊发表SCI学术论文20余篇,发明专利10余项。

代表论著

1.Yixin Zhang, Yanlan Mo, Hongxu Ren, Xiaotong Wu, Liyuan Han, Zhenyuan Sun*, Wenzhong Xu*(corresponding author). Improving Sedum plumbizincicola genetic transformation with the SpGRF4-SpGIF1 gene and the self-excision CRE/LoxP system, Planta, 2024, 259(5)

2.Yixin Zhang, Yanlan Mo, Liyuan Han, Zhenyuan Sun*, Wenzhong Xu*(corresponding author). Exploring transcriptional regulation of hyperaccumulation in Sedum plumbizincicola through integrated transcriptome analysis and CRISPR/Cas9 technology, International Journal of Molecular Sciences, 2023, 24(14)

3.Yixin Zhang, Xiaotong Wu, Yanlan Mo, Liyuan Han, Xin Peng, Zhenyuan Sun*, Wenzhong Xu*(corresponding author). Suppression of highly efficient cadmium translocation by exogenous gibberellin provides insights into the molecular regulation mechanism of hyperaccumulation in Sedum plumbizincicola. Environmental and Experimental Botany, 2023, 209. http://dx.doi.org/10.1016/j.envexpbot.2023. 105296.

4.Qianyu Wang, Jin Zhu, Bing Li, Shanshan Li, Yong Yang, Qingyun Wang, Wenzhong Xu*(corresponding author), Liangsheng Wang*. Functional identification of anthocyanin glucosyltransferase genes: a Ps3GT catalyzes pelargonidin to pelargonidin 3-O-glucoside painting the vivid red flower color of Paeonia. Planta, 2023, 257(4). http://dx.doi.org/10.1007/ s00425-023-04095-2.

5.Shanshan Li, Ling Zhang, Miao Sun, Mengwen Lv, Yong Yang, Wenzhong Xu*(corresponding author), Liangsheng Wang*. Biogenesis of flavor-related linalool is diverged and genetically conserved in tree peony (Paeonia × suffruticosa). Horticulture Research, 2022, 10(2): uhac253. doi: 10.1093/hr/uhac253.

6.Haixia Zhao, Liangsheng Wang, Fang-Jie Zhao, Longhua Wu, Anna Liu, Wenzhong Xu*(corresponding author). SpHMA1 is a chloroplast cadmium exporter protecting photochemical reactions in the Cd hyperaccumulator Sedum plumbizincicola. Plant, Cell & Environment, 2018 Oct 12. doi: 10.1111/pce.13456.

7.Dandan Yin, Shanshan Li, Qingyan Shu, Zhaoyu Gu, Qian Wu, Chengyong Feng, Wenzhong Xu*(corresponding author), Liangsheng Wang*. Identification of microRNAs and long non-coding RNAs involved in fatty acid biosynthesis in tree peony seeds. Gene 2018, 5; 666:72-82.

8.Huan Liu, Haixia Zhao, Longhua Wu, Anna Liu, Fang-Jie Zhao, Wenzhong Xu*(corresponding author). Heavy metal ATPase 3 (HMA3) confers cadmium hypertolerance on the cadmium/zinc hyperaccumulator Sedum plumbizincicola. New Phytologist, 2017, 215(2): 687-698.

9.Huan Liu, Haixia Zhao, Longhua Wu*, Wenzhong Xu*(corresponding author). A genetic transformation method for cadmium hyperaccumulator Sedum plumbizincicola and non-hyperaccumulating ecotype of Sedum alfredii. Frontiers in Plant Science, 2017, 8:1047.

10.Bo Wang, Hong Du, Zhennan Zhang, Wenzhong Xu*(corresponding author), Xin Deng*. BhbZIP60 from Resurrection plant Boea hygrometrica is an mRNA splicing-activated endoplasmic reticulum stress regulator involved in drought tolerance. Frontiers in Plant Science, 2017, 8:245.

11.Dongmei Li, Zhenpeng Guo*, Cuimei Liu, Jincheng Li, Wenzhong Xu, Yi Chen*. Quantification of near-attomole gibberellins in floral organs dissected from a single Arabidopsis thaliana flower. Plant Journal, 2017, 91(3):547-557.

12.Hongmei Xi, Hua Xu, Wenxiu Xu, Zhenyan He, Wenzhong Xu*(corresponding author), Mi Ma*. A SAL1 loss-of-function Arabidopsis mutant exhibits enhanced cadmium tolerance in association with alleviation of endoplasmic reticulum stress. Plant and Cell Physiology, 2016, 57(6): 1210–1219.

13.Wenzhong Xu, Wentao Dai, Huili Yan, Sheng Li, Hongling Shen, Yanshan Chen, Hua Xu, Yangyang Sun, Zhenyan He, Mi Ma*. Arabidopsis NIP3;1 plays an important role in arsenic uptake and root-to-shoot translocation under arsenite stress conditions. Molecular Plant, 2015, 8(5):722-33.

14.Yangyang Sun, Wenzhong Xu(co-first author), Li Wu, Ruozhong Wang, Zhenyan He, Mi Ma*. An Arabidopsis mutant of inositol pentakisphosphate 2-kinase AtIPK1 displays reduced arsenate tolerance. Plant, Cell & Environment, 2016, 39416-426.

15.Zhuoya Zhao, Zenan Xing, Min Zhou, Yi Chen, Chenzhong Li, Ruozhong Wang, Wenzhong Xu*(corresponding author), Mi Ma. Functional analysis of synthetic DELLA domain peptides and bioactive gibberellin assay using surface plasmon resonance technology. Talanta, 2015, 144: 502–509.

16.Hui Dong, Wenzhong Xu, Jitesh K. Pillai, Charles Packianathan, Barry P. Rosen*. High-throughput screening-compatible assays of As(III) S-adenosylmethionine methyltransferase activity. Analytical Biochemistry, 2015, 480:67-73.

17.Zhuoya Zhao, Yanshan Chen, Wenzhong Xu*(corresponding author), Mi Ma. Surface plasmon resonance detection of transgenic Cry1Ac cotton (Gossypium spp.). Journal of Agricultural and Food Chemistry, 2013, 61(12):2964-2969.

18.Yanshan Chen, Wenzhong Xu (co-first author), Hongling Shen, Huili Yan, Wenxiu Xu, Zhenyan He, Mi Ma*. Engineering arsenic tolerance and hyperaccumulation in plants for phytoremediation by a PvACR3 transgenic approach. Environmental Science & Technology,2013, 47 (16): 9355–9362.

19.Hua Xu, Wenzhong Xu(co-first author), Hongmei Xi, Wenwen Ma, Zhenyan He, Mi Ma*. The ER luminal binding protein (BiP) alleviates Cd2+-induced programmed cell death through endoplasmic reticulum stress–cell death signaling pathway in tobacco cells. Journal of Plant Physiology, 2013, 170 (16): 1434–1441.

20.吴俐、王若仲、徐文忠*(通讯作者). 拟南芥中myo-肌醇-多磷酸合成与代谢及其信号. 植物学报, 2013. 48 (1): 94–106.

21.Jiangbo Guo, Wenzhong Xu, Mi Ma*. The assembly of metals chelation by thiols and vacuolar compartmentalization conferred increased tolerance to and accumulation of cadmium and arsenic in transgenic Arabidopsis thaliana. Journal of Hazardous Materials, 2012. 199-200: 309-313.

22.刘安娜、腾瑶、徐文忠*(通讯作者)麻密. 一个编码含VQ 模序蛋白的基因AtARVQ1参与拟南芥对砷酸盐的响应调控. 科学通报, 2011.56(23):1891-1898.

23.Yao Teng, Wenzhong Xu*(corresponding author), Mi Ma. cGMP is required for seed germination in Arabidopsis thaliana. Journal of Plant Physiology, 2010, 167(11):885-9.

24.Beibei Li, Wenzhong Xu(co-first author), Yunyuan Xu, Yuanyuan Zhang, Tai Wang, Yue Bai, Chenggui Han, Aimin Zhang, Zhihong Xu and Kang Chong*. Integrative study on proteomics, molecular physiology, and genetics reveals an accumulation of cyclophilin-like protein, TaCYP20-2, leading to an increase of Rht protein and dwarf in a novel GA-insensitive mutant (gaid) in Wheat. Journal of Proteome Research, 2010, 9(8):4242-53.

25.Wenwen Ma, Wenzhong Xu(co-first author), Hua Xu, Yanshan Chen, Zhenyan He, Mi Ma*. Nitric oxide modulates cadmium influx during cadmium-induced programmed cell death in tobacco BY-2 cells. Planta, 2010, 232(2):325-35.

26.Xuexi Yang, Hui Chen, Xiaojing Dai, Wenzhong Xu, Zhenyan He and Mi Ma*. Evidence of vacuolar compartmentalization of arsenic in the hyperaccumulator Pteris vittata. Chinese Science Bulletin 2009, 54(22): 4229-4233.

27.Jiangbo Guo, Xiaojing Dai, Wenzhong Xu, Mi Ma*. Overexpressing GSH1 and AsPCS1 simultaneously increases the tolerance and accumulation of cadmium and arsenic in Arabidopsis thaliana. Chemosphere 2008, 72: 1020-1026.

28.Yongqiang Zheng, Xiaojing Dai, Lei Wang, Wenzhong Xu, Zhenyan He, Mi Ma*. Arsenate reduces copper phytotoxicity in gametophytes of Pteris vittata. Journal of Plant Physiology 2008, 165: 1906-1916.

29.Yongqiang Zheng, Wenzhong Xu, Zhenyan He, Mi Ma*.  Plant regeneration of the arsenic hyperaccumulator Pteris vittata L. from spores and identification of its tolerance and accumulation of arsenic and copper. Acta Physiologiae Plantarum 2008, 30: 249-255.

30.Xuexi Yang, Hui Chen, Wenzhong Xu, Zhenyan He, Mi Ma*.  Hyperaccumulation of arsenic by callus, sporophytes and gametophytes of Pteris vittata cultured in vitro. Plant Cell Reports 2007, 26: 1889-1897

31.Jiangchuan Li, Jiangbo Guo, Wenzhong Xu, Mi Ma*. RNA interference-mediated silencing of phytochelatin synthase gene reduce cadmium accumulation in rice seeds. Journal of Integrative Plant Biology 2007, 49: 1032-1037.

32.Haiyan Zhang, Wenzhong Xu, Wentao Dai, Zhenyan He, Mi Ma*. Functional characterization of cadmium-responsive garlic gene AsMT2b: a new member of metallothionein family. Chinese Science Bulletin 2006, 51: 409-416.

33.Jiangchuan Li, Jiangbo Guo, Wenzhong Xu, Haiyan Zhang, Mi Ma*. Enhanced cadmium accumulation in transgenic tobacco expressing the phytochelatin synthase gene of Cynodon dactylon. Journal of Integrative Plant Biology 2006, 48: 928-937.

34.詹宝、徐文忠、麻密*. 砷超富集植物蜈蚣草原生质体的分离及其抗砷性分析. 植物学通报 2006, 23(4): 363-367.

35.Haiyan Zhang, Wenzhong Xu, Jiangbo Guo, Zhenyan He, Mi Ma*. Coordinated responses of phytochelatins and metallothioneins to heavy metals in garlic seedlings. Plant Science 2005, 169: 1059-1065.

36.徐文忠、雍伟东、徐云远、梁铁兵、白薇、种康*、谭克辉、许智宏、朱至清. 利用反义RNA技术分析春化相关基因VER17在冬小麦花发育过程中的功能. 植物生理与分子生物学学报 2005, 31: 71-77.

37.孙振元*徐文忠,赵梁军,刘淑兰. pH值和铁素对毛白杜鹃和迎红杜鹃根系Fe3+还原酶活性的影响. 核农学报 2005, 19(6): 456-460.

38.Wenzhong Xu, Xin Wang, Qi Feng, Lei Zhang, Yaoguang Liu, Bin Han, Kang Chong*, Zhihong Xu, Kehui Tan. The VER2 promoter contains repeated sequences and requires vernalization for its activity in winter wheat (Triticum aestivum L.). Chinese Science Bulletin 2004, 49: 355-362.

39.Xin Wang, Wenzhong Xu, Yunyuan Xu, Kang Chong*, Zhihong Xu, Guixian Xia. Wheat RAN1, a nuclear small G protein, is involved in regulation of cell division in yeast. Plant Science 2004, 167: 1183-1190.

40.Weidong Yong, Yunyuan Xu, Wenzhong Xu, Ning Li, Jinsong Wu, Tiebing Liang, Kang Chong*, Zhihong Xu, Kehui Tan. Vernalization-induced flowering in wheat is mediated by a lectin-like gene VER2. Planta 2003, 217: 261-270.

41.孙振元*徐文忠、刘淑兰、赵梁军. 毛白杜鹃耐碱突变体的离体筛选与鉴定. 中南林学院学报 2003, 23(5):53-55.

42.Shiqian Jia, Weidong Yong, Wenzhong Xu, Yunyuan Xu, Jingsong Wu, Kang Chong*, Kehui Tan, Zhihong Xu. Existence of homologous sequences corresponding to cDNA of the ver gene in diverse higher plant species. Cell Research 2001, 11(4):265-271.